WASHINGTON, DC — The apolipoprotein E (APOE) ε2 allele, previously shown to be associated with a lower risk for Alzheimer's disease (AD), is also associated with milder AD pathology after death and ...

Researchers at Niigata University have conducted the first comprehensive reappraisal in nearly 30 years of the risk of ...

Researchers at Niigata University have conducted the first comprehensive reappraisal in nearly 30 years of the risk of ...

Variants in a gene called APOE have long been associated with Alzheimer’s disease (AD) and dementia, but a new study suggests we’ve been seriously underestimating their effect. Per this analysis, two ...

Despite the identification of the APOE gene as the strongest genetic link to late-onset Alzheimer's disease (AD) since 1993 and the subsequent advances in the understanding of AD pathogenesis, the ...

For nearly a quarter-century, researchers have struggled to understand how apolipoprotein E modifies risk for Alzheimer’s disease. A new study offers a beguilingly simple explanation: ApoE elevates ...

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the progressive degradation of brain cells, as well as an associated decline in memory and other mental functions. Earlier ...

When the results are analyzed in terms of relative risk, as done by Farrer and colleagues, [4] the APOE4 allele was found associated with an increased risk of AD, whereas the E2 allele appeared to ...

High-dose DHA effectively increased brain levels in older adults at Alzheimer's risk, but did not lead to cognitive or ...

Does the head honcho of genetic Alzheimer’s risk occlude contributions of smaller genes? In the June 10 JAMA Neurology, researchers led by Lindsay Farrer at Boston University exposed some hidden ...