GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and ...

Explore the breakthrough therapy that offers hope to cure type 1 diabetes by restoring insulin-producing beta cells ...

Researchers are developing a two-part therapy for type 1 diabetes: lab-made insulin-producing cells paired with ...

University of Chicago researchers developed an mRNA nanoparticle system that triggers cells to produce PD-L1 protein, potentially delaying type 1 diabetes progression in animal models.

Lipid nanoparticles deliver mRNA to insulin-producing beta cells, prompting them to express a protective protein that shields them from autoimmune attack.

In recent years, we have come to appreciate that loss or dysfunction of insulin-producing islet beta cells underlies virtually all major forms of diabetes mellitus. In type 1 diabetes, beta cells ...

Borrowing a cancer cell’s disguise, scientists shielded insulin-producing cells from attack by the immune system, a breakthrough that could pave the way for targeted type 1 diabetes treatments without ...

On March 16, Prof. James Lo, pharmacology cell and developmental biology, and his team published a study identifying different types of cells in the pancreas, an organ responsible for aiding digestion ...

An international team of scientists, led by researchers from the Free University of Brussels (VUB) and UZ Brussel, has made a major breakthrough in the study of how our bodies maintain healthy blood ...

Researchers at UChicago have developed a nanoparticle system that can effectively deliver mRNA to insulin-producing cells, protecting them from the body’s autoimmune response ...

Philadelphia researchers at the University of Pennsylvania, working with engineers at Harvard, have wired up lab-grown mini pancreases with hair-thin electronics, nudging immature alpha and beta cells ...

The need to suppress a patient’s immune system after the transplantation of allogeneic cells is associated with wide-ranging side effects. We report the outcomes of transplantation of genetically ...