New treatments for mental health and behavioral disorders are desperately needed. Rates of depression, anxiety, PTSD, and substance use disorders soared during the pandemic, and traditional ...

In November 1956, three people gathered in a converted Connecticut barn to take LSD, a powerful psychedelic drug that was legal at the time. The children had just been put to bed upstairs. In the ...

This article was originally published on Psychedelic Spotlight and appears here with permission. New study suggests that a non-hallucinogenic LSD analog may hold therapeutic potential for mood ...

While trying to understand what makes the psychedelic drug LSD work, Dr. Mattias Liechti, head of the Liechti Laboratory at the University of Basel Hospital, stumbled onto something unexpected. During ...

Scientists have identified a drug that appears to produce the antidepressant effects of LSD without the psychedelic side effects — at least in mice. Drugs like magic mushrooms and LSD can act as ...

Scientists have designed compounds that hit the same key receptor that LSD activates without causing hallucinations. A single dose produced powerful antidepressant and antianxiety effects in mice that ...

Scientists have designed compounds that hit the same key receptor that LSD activates without causing hallucinations. A single dose produced powerful antidepressant and antianxiety effects in mice that ...

Psychedelic pharmaceutical company MindMed has announced the development of a novel compound designed to stop the effects of an LSD experience. The compound is claimed to function as an “off-switch” ...

Editor's note: The following story ran on Page One of the Free Press on March 13, 1966. It has been edited slightly for length. “The first time I got high, I walked ...

LSD was first synthesized by Swiss chemist Albert Hofmann in 1938. He discovered its powerful psychoactive effects in 1943 after accidentally ingesting a small amount and experiencing vivid ...