The biological function of proteins relies on their ability to form structured, ordered complexes such as homo-oligomers or hetero-oligomers. Attributes such as stability, activity, and localization ...
The bulk physical properties such as strength and toughness of materials such as synthetic and natural polymers, or the activity and efficacy of proteins and biopharmaceuticals are strongly dependent ...
Aggregation reduces the active ingredient content in the sample, resulting in a reduction in efficacy Aggregation triggers immunogenic responses in the body. Triggering of immunogenic responses ...
Generally, in protein and peptide analyses, knowing a molecule’s oligomeric state is useful in determining whether the protein exists in its biologically active form. To this end, the first step ...
In natural and synthetic materials, bulk physical properties like toughness and strength mainly rely on their molecular properties. The same concept applies to the efficacy and activity of ...
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