Medically reviewed by William Truswell, MD Nodular acne is a painful, severe form of inflammatory acne that forms hard lumps under your skin.Over-the-counter treatments do not work for nodular acne, ...

Red nodules on the lower legs can sometimes be an early sign of acute myeloid leukemia (AML). AML is a cancer of the blood and bone marrow that is more common in adults over age 55. While AML is a ...