Cleveland Clinic virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how human bodies detect and respond to viruses and viral replication. This ...

A single gram of soil contains between 10 million and 1 billion viruses. Most of those viruses do not infect plants, animals ...

Viral replication relies fundamentally on specialised DNA polymerases that orchestrate genome synthesis, fidelity control and interaction with viral and host factors. These enzymes exhibit remarkable ...

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain. While symptoms can now be better managed with lifelong treatment, there is ...

A research team at Ruhr University Bochum, Germany, has identified a previously unknown cellular mechanism crucial to the replication of coronaviruses: c-Jun N-terminal kinase (JNK) is activated ...

The herpesvirus can manipulate our DNA with far more precision than previously thought. The virus condenses and changes the shape of our genetic material to hijack the host genes needed for ...

Viral infection induces cytoskeleton remodeling into cage-like structure. Virus infection can cause severe rearrangement of the cytoskeleton, and all three kinds of cytoskeleton form a cage-like ...

Most animal viruses never become pandemics because they must overcome multiple barriers, including receptor mismatch, immune ...

To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...

Viruses play a major role in the functioning of ecosystems. They profoundly influence the dynamics of microbial communities, flow of matter and global biogeochemical cycles. Yet despite their ...