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jove.com
Technique of Minimally Invasive Transverse Aortic Constriction in Mice for Induction of Left Ventricular Hypertrophy
Watch this Scientific Journal Video about Technique of Minimally Invasive Transverse Aortic Constriction in Mice for Induction of Left Ventricular Hypertrophy at JoVE.com
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COARCTATION OF THE AORTA (CoA) --- 1--Definition Coarctation of the aorta is a congenital narrowing of the aortic lumen, most commonly located just distal to the origin of the left subclavian artery, near the insertion of the ductus arteriosus (“juxtaductal” area). This narrowing increases afterload and causes upper body hypertension with lower body hypoperfusion. --- 2--Incidence and Epidemiology Occurs in 4–6 per 10,000 live births Accounts for 5–8% of all congenital heart diseases Male : Fema
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