Cytoskeletal filament formation: Scientists discover details about vimentin filaments critical for wound healing
phys.orgOlivia Dimmer
Cytoskeletal filament formation: Scientists discover details about vimentin filaments critical for wound healing
Video of a live MEF cell with vimentin-Y117L-mEmerald droplets showing the dynamic nature of the droplets. Credit: Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas.2418624122
10 months ago
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Vimentin filaments are a key part of the cell’s cytoskeleton, acting as a scaffolding and playing a critical role in helping cells keep their shape and move. These filaments form complex, tightly packed bundles, making it difficult to tease out the behavior of single filaments. Researchers at HHMI’s Janelia Research Campus and Northwestern Medicine used new imaging techniques to get the best look yet at single vimentin filaments, how they are organized and how they move, finding they are more in
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Vimentin filaments are a key part of the cell’s cytoskeleton, acting as a scaffolding and playing a critical role in helping cells keep their shape and move. These filaments form complex, tightly packed bundles, making it difficult to tease out the behavior of single filaments. Researchers at HHMI’s Janelia Research Campus and Northwestern Medicine used new imaging techniques to get the best look yet at single vimentin filaments, how they are organized and how they move, finding they are more in
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